Upcoming events.
UK Kidney Week 2024- CILIAREN session
As part of the ‘Recent research developments in rare and childhood kidney disease’ session, CILIAREN will have its clinical launch at UK Kidney Week 2024 in Edinburgh. Watch this space to hear more.
Pre-clinical Modelling of Human Genetic Disease and Therapy
Organisers: Wendy Bickmore, Luke Boulter, Sara Brown, Pleasantine Mill, Liz Patton and Owen Sansom
Date: 8 – 10 May 2024
Location: Institute of Genetics and Cancer, University of Edinburgh, UK
Rapid advances in gene editing and genetic technologies have revolutionised our ability to model human genetic disease and provided new hope for gene therapies. At this meeting, we will present the very latest advances in modelling human genetic disease, from rare disease, cancer and immune disorders through to genetic modifiers. We will also discuss the latest technologies and the challenges associated with generating relevant human genetic mutations in multi-modal systems, including advanced complex cellular models, model organisms and large animal models, and how genetic technologies can be applied to genome-wide screens and therapy. In addition, speakers will outline the latest strategies to model genetic mutations in cell type and tissue-specific mechanisms, in a developmental and time-dependent fashion, and in the coding and non-coding genome. Importantly, we will also discuss the latest approaches to the phenotyping of models and how to computationally align models with human disease to guide therapeutic intervention and, ultimately, translation.
Speakers
David Adams Wellcome Sanger Institute, UK
James Amatruda Children’s Hospital Los Angeles, USA
Adrian Bird University of Edinburgh, UK
Karen Blyth Beatson Institute for Cancer Research, UK
Ross Cagan University of Glasgow, UK
Ramanuj DasGupta A*STAR Genome Institute of Singapore, Singapore
James Dowling University of Toronto, Canada
Cathy Fernandes King’s College London, UK
Laura Greaves Newcastle University, UK
David Gutmann Washington University School of Medicine, USA
Alberto Kornblihtt University of Buenos Aires, Argentina
Karen Liu King’s College London, UK
Cecilia Lo University of Pittsburgh, USA
Cristina Lo Celso Imperial College London, UK
Malcolm MacLeod University of Edinburgh, UK
Daniel Peeper The Netherlands Cancer Institute, The Netherlands
Steven Pollard University of Edinburgh, UK
Fiona Powrie University of Oxford, UK
Jason Rihel University College London, UK
John Sayer Newcastle University, UK
Robert Semple University of Edinburgh, UK
Angelika Schnieke TUM School of Life Sciences, Technical University of Munich, Germany
Stefan Somlo Yale School of Medicine, USA
Ellen van den Bogaard Radboud University Medical Center, The Netherlands
Eckhard Wolf University of Munich, Germany
Andrew Wood University of Edinburgh, UK
Hao Zhu University of Texas, Southwestern Medical School, USA
Registration: https://www.biologists.com/meetings/dmmgenetics2024/
Rare Diseases Event Newcastle -Renal Disease Workshop
Join us in Newcastle for a face-to-face meeting for MRC NIHR UK Rare Disease Research Network platform nodes focusing on renal ciliopathies (CILIAREN), mTOR Pathway diseases and urinary tract disorders (REOLUT) to explore synergies and opportunities for data sharing and networking, with an emphasis on early career researchers. We have a keynote speaker and opportunities for lightning talks and elevator pitches. We look forward to seeing you!
Location: The Catalyst, Newcastle
Please register for this event and invite your colleagues also.
CILIAREN launch at UK Cilia Network Fall Meeting
Registration is now open for our first in-person UK Cilia Network meeting since lock-down- we look forward to welcoming you in Edinburgh. In addition to guaranteed great science and fantastic interactions, we will also be shaping our ECR network and leadership opportunities in our Executive. Our keynote will be from Prof Dagmar Wachten entitled 'Shedding light on ciliary signaling and function', and we launch our MRC/NIHR CILIA-REN: Renal Ciliopathies National Network, led by Prof John Sayer.
The event is free thanks to our generous sponsors Ciliopathy Alliance, Company of Biologists, Epithelix, Proteintech and CILIAREN.
To join us, please complete this registration form (https://forms.office.com/e/EtTDAeGaFY). Registration closes 29/09/2023 12:00 noon.
UK CILIA NETWORK FALL MEETING
Date: October 6th, 2023 11:00 - 17:45
Place: IGC, University of Edinburgh, Western General Campus, EH4 2XU
11:00–12:00 Arrival, brunch, posters
Session I
12:00–12:05 Welcome, Pleasantine Mill
12:05–12:25 Viviana Macarelli (PhD student, Merkle lab, Cambridge) Characterisation of short sequences that target proteins to the primary cilia membrane across diverse cell types
12:25–12:45 Anu Sironen (Postdoc, Mitchison lab, ICH UCL) Male specific motile cilia in efferent ducts
12:45-13:05 Daniel Baird (PhD student, Larsen lab, Copenhagen) TAK1 and TAB2 operate at the primary cilium to coordinate heart development.
13:05–13:25 Kateřina Apolínová (PhD student, ZeClinics, Barcelona) A novel platform for unraveling the role of the primary cilium in heart regeneration
13:25–13:45 Mathieu Bottier (Research Associate, Hogg lab, Royal Brompton Hospital) Use of Computer Vision Artificial Intelligence for the diagnosis of Primary Ciliary Dyskinesia
13:45-14:00 Ciliopathy Alliance talk and questions
14:00-14:45 Coffee break/posters
Session II
14:45–14:50 Welcome, Girish Mali
14:50–15:05 CILIAREN, Renal Ciliopathies National Network launch, John Sayer (Newcastle)
15:05–15:25 Katarzyna Szymanska (Postdoc, Johnson lab, Leeds) Developing new treatments for cystic kidney disease.
15:25-15:45 Francesco Boselli (Boselli lab, Durham) Ciliary alignment through flow-induced cellular rearrangements in mosaic tissues.
16:05–16:25 Analle Abuammar (RA, Mennella lab, Cambridge) Development of an automated pipeline for segmentation of ciliated cells from Volume Electron Microscopy data
16:25–16:45 Beth Cutting (PhD student, Knight lab, Queen Mary University of London) Development of a kidney organ-chip model to study therapeutic regulation of primary cilia mechanobiology
16:45-17:15 Keynote: Dagmar Wachten (Bonn) Shedding light on ciliary signaling and function
17:15-17:30 UK Cilia Network update, ECR elections and close